The luxurious 31-roomed Protea Hotel Mossel Bay is a graceful landmark, built in 1846, overlooking Santos Bay and harbour. Nestling on the Mossel Bay shoreline with the majestic Outeniqua mountains as a backdrop, the Protea Hotel Mossel Bay is singled out from other establishments.

The stone walls and Mediterranean-style out-buildings belie the fact that the main building is one of the oldest in Mossel Bay and forms part of the Dias Museum Complex. Previously The Old Post Office Tree Manor Hotel, the Protea Hotel Mossel Bay, situated off Santos beach, could best be described as a hotel complex. It comprises of a breakfast patio with sea view, the Cafe Gannet Seafood Restaurant - "Mossel Bay's Seafood House", overlooking the Bay and Outeniqua Mountains. The Blue Oyster cocktail bar, adjacent to the pool, overlooks Munro's Bay and Jacana curio shop.

Added attractions are the close proximity to shopping facilities, the yacht club, harbour and north-facing, sun splashed beaches. As part of the museum complex, the Maritime, Local History and Shell Museum, as well as the Old Post Office Tree, are all within strolling distance. The new golf estate is 2km away and the airport a 20 minute drive.